drugset / Trial / NCT06059144

Induced Hypertension in Acute PRogrESsive Perforating Artery Stroke Using Peripheral Dilute noREpinephrine

NCT06059144

Phase 3 Recruiting 358 enrolled University Hospital, Bordeaux
RandomizedParallel-groupSingle-blindTreatment

Summary

PRESSURE is a multicenter, prospective, randomized, open, blinded end-point assessed (PROBE) trial, that aims to evaluate the efficacy and safety of drug-induced hypertension using peripheral dilute norepinephrine, in patients with acute ischemic stroke in a perforating artery territory and experiencing early neurological deterioration.

Timeline

Start
2024-11-28
Primary completion
2027-08-28
Completion
2027-11-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Norepinephrine Other / unclassified 0.04 ug/kg Intravenous

Indications