drugset
drugset / Trial / NCT05193968

Hot Flashes and Neurovascular Function in Women

NCT05193968 ↗

Recruiting 120 enrolled Mayo Clinic National Heart, Lung, and Blood Institute (NHLBI) · collabNational Institutes of Health (NIH) · collab
NaSingle-groupOpen-labelBasic science

Summary

Women who experience hot flashes are at greater risk for hypertension and other cardiovascular disease. Neurovascular control mechanisms are likely to play an important role in this relationship. As such, these studies are designed to provide a major step forward in understanding the link between hot flashes and neurovascular dysfunction and, by extension, cardiovascular disease in women.

Timeline

Start
2022-02-24
Primary completion
2026-12
Completion
2026-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Acetylcholine Small molecule 1 unknown Other
Subject Acetylcholine Small molecule 2 unknown Other
Subject Acetylcholine Small molecule 4 unknown Other
Subject Acetylcholine Small molecule 8 unknown Other
Subject Norepinephrine Other / unclassified 1 unknown Other
Subject Norepinephrine Other / unclassified 2 unknown Other
Subject Norepinephrine Other / unclassified 4 unknown Other
Subject Norepinephrine Other / unclassified 8 unknown Other
Subject Sodium Nitroprusside Unknown 0.25 unknown Other
Subject Sodium Nitroprusside Unknown 0.5 unknown Other
Subject Sodium Nitroprusside Unknown 1 unknown Other
Subject Sodium Nitroprusside Unknown 2 unknown Other
Subject Terbutaline Small molecule 0.1 unknown Other
Subject Terbutaline Small molecule 0.5 unknown Other
Subject Terbutaline Small molecule 1 unknown Other
Subject Terbutaline Small molecule 2 unknown Other

Indications

No indication recorded.