drugset / Trial / NCT05665881

Effects of Vasopressors on Cerebral Hemodynamics in Patients With Carotid Endarterectomy (TCD Part)

NCT05665881

Completed 90 enrolled Beijing Tiantan Hospital
RandomizedParallel-groupDouble-blindTreatment

Summary

This study was a single-center, exploratory, randomized controlled trial. First, the effects of ephedrine, phenylephrine, or norepinephrine on cerebral blood flow hemodynamics in patients undergoing carotid endarterectomy were evaluated using TCD techniques to investigate the specific mechanisms of the three vasopressors on cerebral blood flow and oxygen metabolism in brain tissues.

Timeline

Start
2023-01-07
Primary completion
2024-09-24
Completion
2024-09-24

Drugs

EvaluationDrugModalityDoseRoute
Subject Ephedrine Small molecule
Subject Norepinephrine Other / unclassified Intravenous
Subject Phenylephrine Small molecule Intravenous

Indications