drugset / Trial / NCT07796282
Superiority of Phenylephrine Versus Norepinephrine in Complex Spine Surgery (SPiNeS)
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this research is to compare two commonly used medications, phenylephrine and norepinephrine, that are used to treat low blood pressure during complex spine surgery. The goal is to determine whether one medication better maintains blood flow to the body's organs during surgery and whether it leads to better recovery and fewer complications after surgery.
Timeline
- Start
- 2026-09
- Primary completion
- 2028-05
- Completion
- 2028-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Norepinephrine | Other / unclassified | 0.02 ug/kg | — |
| Comparator | Phenylephrine | Small molecule | 0.2 ug/kg | — |
Indications
No indication recorded.