Norepinephrine Prophylaxis for Postspinal Anesthesia Hypotension in Parturients With Preeclampsia.

Completed 180 enrolled General Hospital of Ningxia Medical University

RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to investigate the suitable infusion dose of norepinephrine for prophylaxis against postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean section.

Timeline

Start: 2021-11-16
Primary completion: 2023-06-06
Completion: 2023-06-06

Publications

Chen Y, Guo L, Qin R, Xi N, Wang S, Ma Y, Ni X. Dose-Response Study of Norepinephrine Infusion for Maternal Hypotension in Preeclamptic Patients Undergoing Cesarean Delivery Under Spinal Anesthesia. Clin Pharmacokinet. 2024 Jun;63(6):847-856. doi: 10.1007/s40262-024-01381-4. Epub 2024 Jun 13.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Norepinephrine	Other / unclassified	0.025 ug/kg	—
Subject	Norepinephrine	Other / unclassified	0.05 ug/kg	—
Subject	Norepinephrine	Other / unclassified	0.075 ug/kg	—

Indications

No indication recorded.