Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery

Phase 4 Completed 45 enrolled Marc Tewfik

RandomizedParallel-groupSingle-blindOther

Summary

The purpose of our study is to assess the effect of topical vasoconstriction (cocaine 4% versus adrenaline 1/1000) on the surgical field during endoscopic sinus surgery.

Timeline

Start: 2012-12
Primary completion: 2013-12
Completion: 2013-12

Publications

Results Valdes CJ, Bogado M, Rammal A, Samaha M, Tewfik MA. Topical cocaine vs adrenaline in endoscopic sinus surgery: a blinded randomized controlled study. Int Forum Allergy Rhinol. 2014 Aug;4(8):646-50. doi: 10.1002/alr.21325. Epub 2014 Mar 26.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Cocaine	Small molecule	4 %	Intranasal
Subject	Epinephrine	Other / unclassified	0.1 %	Intranasal

Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery

Summary

Timeline

Publications

Drugs

Indications