drugset / Trial / NCT01708369

Alcohol Inhibits Drug Metabolism by Carboxylesterases

NCT01708369

Phase 1 Completed 19 enrolled University of Tennessee
RandomizedCrossoverOpen-labelBasic science

Summary

The purpose of this study is to determine if alcohol is able the affect the body's ability to eliminate two commonly used medication, oseltamivir and aspirin. We hypothesize that drinking alcohol may reduce the body's ability to break down these two medications along with many others.This could affect the amount of drug in the blood which could impact how well these drugs work and whether patients have side effects.

Timeline

Start
2012-02
Primary completion
2012-05
Completion
2012-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Alcohol Other / unclassified Oral
Subject Aspirin Small molecule 650 mg Oral
Subject Oseltamivir Small molecule 150 mg Oral

Indications

No indication recorded.