The Effect of Administration of Low Dose Adrenaline During Surgery on Bleeding During Hip Surgery

Phase 3 Completed 106 enrolled Rigshospitalet, Denmark

RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to evaluate the effect of intraoperative administration of low-dose adrenaline on intraoperative blood loss in patients undergoing hip surgery.

Timeline

Start: 2012-11
Primary completion: 2013-09
Completion: 2013-09

Publications

Jans O, Grevstad U, Mandoe H, Kehlet H, Johansson PI. A randomized trial of the effect of low dose epinephrine infusion in addition to tranexamic acid on blood loss during total hip arthroplasty. Br J Anaesth. 2016 Mar;116(3):357-62. doi: 10.1093/bja/aev408. Epub 2016 Jan 27.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Epinephrine	Other / unclassified	0.05 ug/kg	Intravenous

Indications

No indication recorded.