drugset / Trial / NCT01711671

A Study of DKN-01 and Lenalidomide/Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

NCT01711671

Phase 1 Completed 8 enrolled Leap Therapeutics, Inc.
RandomizedParallel-groupOpen-labelTreatment

Summary

A study to evaluate the safety, efficacy and bone changes with combination therapy of intravenous (IV) infused DKN-01 and lenalidomide/dexamethasone, versus lenalidomide and dexamethasone in relapsed or refractory multiple myeloma (MM) patients

Timeline

Start
2013-05
Primary completion
2015-07
Completion
2015-07

Drugs

EvaluationDrugModalityDoseRoute
Subject DKN-01 Monoclonal antibody 300 mg Intravenous
Subject DKN-01 Monoclonal antibody 600 mg Intravenous
Comparator Dexamethasone Small molecule
Comparator Lenalidomide Other / unclassified

Indications