drugset / Trial / NCT01712061

A Phase 2 Multi-Center Study To Evaluate The Efficacy And Safety Of A Chemokine CCR2/5 Receptor Antagonist In Adults With Type 2 Diabetes And Overt Nephropathy

NCT01712061

Phase 2 Completed 226 enrolled Pfizer
RandomizedParallel-groupDouble-blindTreatment

Summary

The study hypothesis under test is that administration of a CCR2/5 antagonist to subjects with type 2 diabetes and overt nephropathy will result in a reduction in urinary albumin, a surrogate for improved glomerular filtration.

Timeline

Start
2012-12
Primary completion
2014-09
Completion
2014-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator PF-04634817 Small molecule 150 mg
Comparator PF-04634817 Small molecule 200 mg