Efficacy of Alkalinized Lidocaine in the Endotracheal Tube Cuff on the Incidence of Coughing During Emergence

Summary

This study is designed to compare the efficacy of endotracheal tube cuffs pre-filled with alkalinized lidocaine on the: * incidence of coughing during emergence of general anesthesia * time needed for emergence following a desflurane-based anesthesia * incidence of sore throat after extubation. The investigator's hypothesis is that the use of endotracheal tube cuffs pre-filled with alkalinized lidocaine will reduce the incidence of coughing by 50% relative to a control group following a desflurane-based anesthesia.

Timeline

Start

2013-01

Primary completion

2014-04

Completion

2014-04

Publications

• Nath P, Williams S, Herrera Mendez LF, Massicotte N, Girard F, Ruel M. Alkalinized Lidocaine Preloaded Endotracheal Tube Cuffs Reduce Emergence Cough After Brief Surgery: A Prospective Randomized Trial. Anesth Analg. 2018 Feb;126(2):615-620. doi: 10.1213/ANE.0000000000002647.

Drugs

Indications

No indication recorded.