drugset / Trial / NCT01724476
A Trial of Folate With B12 in Patients With Schizophrenia With Residual Symptoms in Ethiopia
Phase 4
Completed
200 enrolled
Massachusetts General Hospital
Addis Ababa University · collabAmanuel Mental Hospital, Addis Ababa, Ethiopia · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The investigators propose to conduct a randomized Sequential Parallel Design for Double-Blind Phase fixed dose, 4-month trial of folate plus B12 as add-on therapy in 200 Ethiopian subjects with schizophrenia with stable residual positive or negative symptoms.
Timeline
- Start
- 2014-12
- Primary completion
- 2017-03
- Completion
- 2017-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | B12 | Other / unclassified | 400 ug | — |
| Comparator | folic acid | Small molecule | 2 mg | — |