Drugs / folic acid
folic acid
also known as
Folate · Acide folique · Acido folico · Acidum folicum · B03BB01 · Bio science · Folacin · Folate or folic acid · +25 more
Trials 9 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 22 trials | ||||||
| Phase 2 | NCT02773147 | Apr 2016 → Nov 2018 | HIV infectious disease | Göteborg University | Unknown | No outcome recorded |
| Phase 2 | NCT00054938 | Mar 2003 → Dec 2005 | systemic lupus erythematosus | Brigham and Women's Hospital | Completed | No outcome recorded |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT00272324 | Feb 1992 → Jan 2007 | colon adenoma, colorectal cancer, polyp of colon | Dartmouth-Hitchcock Medical Center | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT00056225 | Jan 2003 → Jun 2007 | Alzheimer disease | National Institute on Aging (NIA) | Completed | No outcome recorded |
| Phase 44 trials | ||||||
| Phase 4 | NCT07592897 | Jun → Nov 2026 expected | — | University of Sao Paulo | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT07523646 | May 2026 → Apr 2028 expected | anemia, infective endocarditis | Rigshospitalet, Denmark | Recruiting | No outcome recorded |
| Phase 4 | NCT00226356 | Dec 2004 → Jun 2007 | major depressive disorder | Cambridge Health Alliance | Completed | No outcome recorded |
| Phase 4 | NCT00249288 | Dec 2003 → Jun 2008 | schizophrenia | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT03073590 | Jan 2016 → Jun 2017 | anemia | International Centre for Diarrhoeal Disease Research, Bangladesh | Completed | No outcome recorded |
Also used as a comparator or background therapy in 9 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 22 trials | ||||||
| Phase 2 | NCT00227019 Background | Mar 2006 → Nov 2010 | metastatic neoplasm, non-small cell lung carcinoma | Heather Wakelee | Completed | No outcome recorded |
| Phase 2 | NCT00243412 Background | Aug 2005 → Feb 2009 | rheumatoid arthritis | Genentech, Inc. | Completed | No outcome recorded |
| Phase 34 trials | ||||||
| Phase 3 | NCT02576067 Background | Dec 2015 → Mar 2019 | atherosclerotic cardiovascular disease, vasculitis | Icahn School of Medicine at Mount Sinai | Completed | No outcome recorded |
| Phase 3 | NCT00299104 Background | Jan 2006 → Sep 2008 | rheumatoid arthritis | Genentech, Inc. | Completed | No outcome recorded |
| Phase 3 | NCT00266227 Background | Jan 2006 → Oct 2007 | rheumatoid arthritis | Genentech, Inc. | Completed | No outcome recorded |
| Phase 3 | NCT00299130 Background | Oct 2005 → Jun 2008 | rheumatoid arthritis | Genentech, Inc. | Completed | No outcome recorded |
| Phase 43 trials | ||||||
| Phase 4 | NCT05288153 Comparator | Apr 2022 → May 2023 | gastric intestinal metaplasia | Xijing Hospital of Digestive Diseases | Completed | No outcome recorded |
| Phase 4 | NCT01724476 Comparator | Dec 2014 → Mar 2017 | schizophrenia | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 4 | NCT01283971 Background | May 2011 → Aug 2012 | rheumatoid arthritis | Hoffmann-La Roche | Terminated | No outcome recorded |
Press releases naming this drug 3 releases
| Date | Issuer | Release |
|---|---|---|
| 2015-11-08 | AbbVie | Treatment Response to ImmunoGen's Mirvetuximab Soravtansine Found to be Substantially Greater in Ovarian Cancer with High Expression of Folate Receptor Alpha abbvie.com ↗ |
| 2012-07-11 | AbbVie | ImmunoGen, Inc. Initiates Phase I Trial of IMGN853 in Ovarian Cancer and Other Solid Tumors Over-Expressing Its Folate Receptor Target abbvie.com ↗ |
| 2012-04-17 | AbbVie | ImmunoGen, Inc. Announces the IND Is Now Active for Its Folate-Receptor Targeting Anticancer Compound, IMGN853 abbvie.com ↗ |
Evidence & citations 37 cited values
Every value below carries the sentence it was read from. 19 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | folic acid | “high-dose folate (folic acid), B6, and B12 supplementation” NCT00056225 ↗1“Folate (folic acid) - 400 mcg” NCT07592897 ↗ |
| Known as | Acide folique | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Acido folico | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Acidum folicum | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | B03BB01 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Bio science | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Folacin | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Folate | “the intervention will consist of the twice weekly provision of iron/folate supplements to female workers, and the enhanced BCC program, as described above.” NCT03073590 ↗17“Vitamin supplementation (i.e. multivitamin, vitamin B12 and/or folate) will follow Danish clinical recommendations.” NCT07523646 ↗ “Study participants will additionally receive 1 mg daily oral folate.” NCT02576067 ↗ “Folate (folic acid) - 400 mcg” NCT07592897 ↗ |
| Known as | Folate or folic acid | “Folate or folic acid” NCT00249288 ↗ |
| Known as | FOLATE SODIUM | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Foldine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Folettes | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Foliamin | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Folic acid component of folvron | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Folic acid component of vitaped | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Folic acid sodium salt | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Folic acid, monosodium salt | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Folicare | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Folicet | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Folipac | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Folsan | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Folvite | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Incafolic | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Lexpec | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Millafol | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Natur flow | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | NSC-3073 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Preconceive | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Roche | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Sodium folate | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Sodium pteroylglutamate | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Vitamin b9 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Vitamin bc | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Known as | Vitamin m | ChEMBL registry synonym — accepted as the source's own label CHEMBL1622 ↗ |
| Action | Inhibit | “homocysteine levels can be reduced by administration of high dose supplements of folate (folic acid) and vitamins B6 and B12” NCT00056225 ↗ |
| Modality | Small molecule | — CHEMBL1622 ↗ |
| Route | Oral | “Minimum of 1 mg/day oral” NCT00243412 ↗ |