Prostate Cancer Active Surveillance Metformin Trial

Summary

To determine whether the use of metformin in patients with low-risk prostate cancer can delay progression to clinically significant prostate cancer.

Timeline

Start

2013-01

Primary completion

2014-10

Completion

2014-10

Outcome

Outcome not reported

Stopped: “The reason for this decision is that this study is being merged with a larger multi-centre study using the same agent in the same population.”

Publications

• Roy S, Malone S, Grimes S, Morgan SC. Impact of Concomitant Medications on Biochemical Outcome in Localised Prostate Cancer Treated with Radiotherapy and Androgen Deprivation Therapy. Clin Oncol (R Coll Radiol). 2021 Mar;33(3):181-190. doi: 10.1016/j.clon.2020.09.005. Epub 2020 Sep 29.

Drugs

Indications