drugset / Trial / NCT01734824
Treatment of Atraumatic Bone Marrow Edema With Denosumab and Teriparatide vs Placebo
RandomizedParallel-groupSingle-blindTreatment
Summary
The etiology of bone marrow edema (BME) is still uncertain. Several studies report therapeutic success with antiresorptive drugs. This study investigates antiresorptive and osteoanabolic drugs versus placebo in BME
Timeline
- Start
- 2012-05
- Primary completion
- 2015-09
- Completion
- 2015-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Denosumab | Monoclonal antibody | 60 mg | Subcutaneous |
| Comparator | Teriparatide | Protein / enzyme biologic | 20 ug | Subcutaneous |