drugset / Trial / NCT01738724

Study of the Efficacy of Dienogest in the Treatment of Uterine Leiomyomas When Compared to Desogestrel and Goserelin

NCT01738724

Phase 4 Terminated 14 enrolled University of Sao Paulo
RandomizedParallel-groupOpen-labelTreatment

Summary

The investigators´aim is to assess whether the progestagen dienogest reduces leiomyoma volume and its associated symptoms to the same extent as gonadotropin releasing hormone (GnRH) analogs or the progestagen desogestrel or whether it is inferior to other drugs already in use.

Timeline

Start
2012-01
Primary completion
2016-12
Completion
2017-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Desogestrel Small molecule 75 ug Oral
Subject Dienogest Small molecule 2 mg Oral
Subject Goserelin Other / unclassified 10.8 mg Subcutaneous

Indications