drugset / Trial / NCT01738724
Study of the Efficacy of Dienogest in the Treatment of Uterine Leiomyomas When Compared to Desogestrel and Goserelin
RandomizedParallel-groupOpen-labelTreatment
Summary
The investigators´aim is to assess whether the progestagen dienogest reduces leiomyoma volume and its associated symptoms to the same extent as gonadotropin releasing hormone (GnRH) analogs or the progestagen desogestrel or whether it is inferior to other drugs already in use.
Timeline
- Start
- 2012-01
- Primary completion
- 2016-12
- Completion
- 2017-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Desogestrel | Small molecule | 75 ug | Oral |
| Subject | Dienogest | Small molecule | 2 mg | Oral |
| Subject | Goserelin | Other / unclassified | 10.8 mg | Subcutaneous |