Bone Metabolism After Laparoscopic Gastric Bypass Surgery (BABS)

Phase 2 Completed 160 enrolled Medical University of Vienna

RandomizedParallel-groupOpen-labelTreatment

Summary

Bariatric surgery leads to rapid weight loss in female and male patients. Less data are available about its impact on bone metabolism. The aim of this study is the investigation of changes in bone mineral density,bone histomorphometric changes, serum bone turnover markers and changes in body fat and muscle composition in patients after laparoscopic gastric bypass surgery.

Timeline

Start: 2012-11
Primary completion: 2014-07
Completion: 2014-08

Publications

Muschitz C, Kocijan R, Haschka J, Zendeli A, Pirker T, Geiger C, Muller A, Tschinder B, Kocijan A, Marterer C, Nia A, Muschitz GK, Resch H, Pietschmann P. The Impact of Vitamin D, Calcium, Protein Supplementation, and Physical Exercise on Bone Metabolism After Bariatric Surgery: The BABS Study. J Bone Miner Res. 2016 Mar;31(3):672-82. doi: 10.1002/jbmr.2707. Epub 2015 Sep 30.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Calcium carbonate	Other / unclassified	500 mg	Oral
Comparator	Vitamin D	Other / unclassified	16000 iu	Oral

Indications

No indication recorded.