Indomethacin Prophylaxis for Heterotopic Ossification After Surgical Treatment of Elbow Trauma

Unknown 150 enrolled London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Patients who present to our institution with a traumatic injury to their elbow who need operative management will be randomized to one of two groups; a treatment arm and a control arm. The treatment arm will receive a three-week postoperative course of indomethacin while the control group will not. We will follow both groups to assess whether or not indomethacin prophylaxis affects the rate of heterotopic ossification.

Timeline

Start: 2012-11
Primary completion: 2019-11
Completion: 2019-11

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Indomethacin	Small molecule	25 mg	—
Background	Pantoprazole	Other / unclassified	40 mg	—

Indications

No indication recorded.