Efficacy and Tolerability of Lidocaine Plaster for Treatment of Long-term Local Nerve Pain

Summary

The purpose of this trial is to investigate the efficacy and safety of lidocaine 5% medicated plaster in localized chronic post-operative neuropathic pain in comparison to placebo plaster.

Timeline

Start

2012-10

Primary completion

2016-06

Completion

2016-06

Outcome

Missed primary endpoint

paper but the difference was not statistically significant (-0.23 [0.23], [-0.69, 0.22]). PMID 30614286 ↗

Publications

• Palladini M, Boesl I, Koenig S, Buchheister B, Attal N. Lidocaine medicated plaster, an additional potential treatment option for localized post-surgical neuropathic pain: efficacy and safety results of a randomized, placebo-controlled trial. Curr Med Res Opin. 2019 May;35(5):757-766. doi: 10.1080/03007995.2019.1565709. Epub 2019 Jan 21.

Drugs

Indications