drugset / Trial / NCT01757795
Safety, Tolerability and Pharmacokinetics of SP-8203
RandomizedParallel-groupDouble-blindTreatment
Summary
Phase I study in health volunteers to assess the safety, tolerability and pharmacokinetics of escalating single doses and multiple doses of SP-8203
Timeline
- Start
- 2013-12-23
- Primary completion
- 2015-03-11
- Completion
- 2015-03-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | OTAPLIMASTAT | Small molecule | 10 mg | Intravenous |
| Subject | OTAPLIMASTAT | Small molecule | 20 mg | Intravenous |
| Subject | OTAPLIMASTAT | Small molecule | 40 mg | Intravenous |
| Subject | OTAPLIMASTAT | Small molecule | 80 mg | Intravenous |
| Subject | OTAPLIMASTAT | Small molecule | 160 mg | Intravenous |
| Subject | OTAPLIMASTAT | Small molecule | 240 mg | Intravenous |