drugset
drugset / Trial / NCT01764555

Pharmacokinetics of Acetaminophen in Morbidly Obese Patients

NCT01764555 ↗

Phase 4 Completed 28 enrolled St. Antonius Hospital
Non-randomizedSingle-groupOpen-labelBasic science

Summary

This study will investigate the pharmacokinetics of acetaminophen in morbidly obese patients versus normal weight patients. Specifically the different metabolic pathways of acetaminophen in morbidly obese adults will be investigated; glucuronidation, sulphation and CYP2E1 (cytochrome P450 2E1) oxidation

Timeline

Start
2012-12
Primary completion
2014-03
Completion
2014-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Acetaminophen Small molecule 2 g Intravenous

Indications

morbid obesity