Erivedge (Vismodegib) in the Treatment of Pediatric Patients With Refractory Pontine Glioma

Summary

The purpose of this research study is to evaluate an investigational drug (Vismodegib) for Pontine Glioma that is growing or has come back (reoccurred). This study will look at the tumors response to the study drug, Vismodegib, and will also look at the safety and tolerability of Vismodegib. Vismodegib has been tested in multiple adult clinical trials and one pediatric trial. Laboratory testing in pontine gliomas suggests that this drug may be effective in treating this disease.

Timeline

Start

2013-05

Primary completion

2015-10

Completion

2015-10

Drugs

Indications