drugset / Trial / NCT01774578

Immunotherapy Study in Progressive or Relapsed Non-Small Cell Lung Cancer

NCT01774578

Phase 2/3 Terminated 135 enrolled NewLink Genetics Corporation
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to assess overall survival of anti-tumor immunization using HyperAcute®-Lung immunotherapy versus Docetaxel in patients with progressed or relapsed non-small cell lung cancer (NSCLC) that have been previously treated.

Timeline

Start
2013-02
Primary completion
2016-05-18
Completion
2016-06-18

Drugs

EvaluationDrugModalityDoseRoute
Subject Docetaxel Small molecule 75 mg/m2 Intravenous
Subject Tergenpumatucel-L Vaccine 3e+08 cells Intramuscular
Background Gemcitabine Small molecule 1250 mg/m2
Background Pemetrexed Small molecule 500 mg/m2