drugset / Trial / NCT01775579
Evaluating a Pharmacokinetic Drug Interaction Between Metformin Hydrochloride and Rosuvastatin Calcium
RandomizedCrossoverOpen-labelTreatment
Summary
We investigate the potential pharmacokinetic drug-drug interaction between metformin extended release and rosuvastatin in healthy male volunteers who receive metformin extended release alone, rosuvastatin alone, and both together in a 3 period repeatedly.
Timeline
- Start
- 2013-01
- Primary completion
- 2013-03
- Completion
- 2013-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metformin | Small molecule | 750 mg | — |
| Subject | Rosuvastatin | Small molecule | 20 mg | — |