drugset / Trial / NCT01778192

A Randomized Prospective Trial Comparing Polyethylene Glycol and Sodium Picosulphate With Magnesium Citrate

NCT01778192

Phase 3 Completed 200 enrolled Korea University Anam Hospital
RandomizedParallel-groupSingle-blindSupportive care

Summary

Adequate bowel cleansing is important for a completeness of colonoscopy and detection of colon polyps. Inadequate bowel preparation leads to longer duration of colonoscopy and obscured mucosal visualization resulting in missed lesions. Bowel cleansing agents are simply classified into the large volume, iso-osmotic polyethylene glycol (PEG) based solutions or the small volume osmotically active agents, such as sodium picosulphate with magnesium citrate (SPMC). There are rare reports that compare directly conventional polyethylene glycol (PEG) solution and sodium picosulphate with magnesium citrate (SPMC) for bowel preparation in korea. The aim of this study is to compare the efficacy, safety, and tolerability of different regimens of SPMC and PEG solution.

Timeline

Start
2012-07
Primary completion
2012-11
Completion
2012-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Sodium picosulphate with magnesium citrate Unknown
Comparator polyethylene glycol Other / unclassified 2000 ml
Comparator polyethylene glycol Other / unclassified 4000 ml