drugset / Trial / NCT01782976

Ph II Cilengitide Plus Bevacizumab for Recurrent Glioblastoma (GBM)

NCT01782976

NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical research study is to learn if cilengitide given in combination with bevacizumab can help to control glioblastoma. The safety of this drug combination will also be studied. Cilengitide is designed to block the flow of blood to cancer cells, which may help to slow or block the growth of cancer. Bevacizumab is designed to block the growth of new blood vessels, which may help to slow or block the growth of cancer.

Timeline

Start
2013-06
Primary completion
2017-06
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 10 mg/kg Intravenous
Subject cilengitide Peptide 2000 mg Intravenous

Indications