drugset / Trial / NCT01782976
Ph II Cilengitide Plus Bevacizumab for Recurrent Glioblastoma (GBM)
Phase 2
Withdrawn
M.D. Anderson Cancer Center
Brain Tumor Trials Collaborative · collabEMD Serono · collab
NaSingle-groupOpen-labelTreatment
Summary
The goal of this clinical research study is to learn if cilengitide given in combination with bevacizumab can help to control glioblastoma. The safety of this drug combination will also be studied. Cilengitide is designed to block the flow of blood to cancer cells, which may help to slow or block the growth of cancer. Bevacizumab is designed to block the growth of new blood vessels, which may help to slow or block the growth of cancer.
Timeline
- Start
- 2013-06
- Primary completion
- 2017-06
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bevacizumab | Monoclonal antibody | 10 mg/kg | Intravenous |
| Subject | cilengitide | Peptide | 2000 mg | Intravenous |