drugset / Trial / NCT01786200
Physiological Effects of Altering Cancer-related Inflammation
Unknown
60 enrolled
NHS Greater Glasgow and Clyde
Academy of Medical Sciences · collabWellcome Trust · collab
RandomizedParallel-groupOpen-labelBasic science
Summary
This prospective pilot study will examine whether the previously reported effects of NSAIDs on colorectal cancer may be modulated through alterations in tissue gene expression, up regulation of local immune cell infiltrates or down-regulation of the systemic inflammatory response.
Timeline
- Start
- 2013-02
- Primary completion
- 2014-12
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Aspirin | Small molecule | 75 mg | Oral |
| Comparator | Ibuprofen | Small molecule | 400 mg | Oral |