drugset / Trial / NCT01789047
Topiramate as an Adjunct to Amantadine in the Treatment of Dyskinesia in Parkinson's Disease
Phase 2
Terminated
42 enrolled
Rush University Medical Center
Michael J. Fox Foundation for Parkinson's Research · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The study will involve an eighteen-week, double-blind, placebo-controlled parallel designed comparison between add-on topiramate and add-on placebo to stable treatment with amatadine in the treatment of Parkinson's disease (PD) patients who continue to have dyskinesia on amantadine.
Timeline
- Start
- 2013-03
- Primary completion
- 2016-07
- Completion
- 2016-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Topiramate | Small molecule | — | — |
| Comparator | Amantadine | Unknown | — | — |