Single Dose of Etomidate and Adrenal Cortex

NCT01792037 ↗

Phase 4 Completed 90 enrolled Istanbul University

RandomizedCrossoverSingle-blindPrevention

Summary

we aim to evaluate the effects of single dose of etomidate or use of steroid prior to etomidate during emergency intubation on hemodynamics and adrenal cortex.

Timeline

Start: 2012-12
Primary completion: 2013-03
Completion: 2013-03

Publications

Background Tekwani KL, Watts HF, Sweis RT, Rzechula KH, Kulstad EB. A comparison of the effects of etomidate and midazolam on hospital length of stay in patients with suspected sepsis: a prospective, randomized study. Ann Emerg Med. 2010 Nov;56(5):481-9. doi: 10.1016/j.annemergmed.2010.05.034. Epub 2010 Sep 15.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Etomidate	Small molecule	0.3 mg/kg	Intravenous
Comparator	Methylprednisolone	Other / unclassified	2 mg/kg	Intravenous
Comparator	Midazolam	Small molecule	0.01 mg/kg	Intravenous

Single Dose of Etomidate and Adrenal Cortex

Summary

Timeline

Publications

Drugs

Indications