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drugset / Trial / NCT01797900

The Role of Induction Chemotherapy for High-risk Locally Advanced Nasopharyngeal Carcinoma in the Era of IMRT

NCT01797900 ↗

Phase 2 Completed 130 enrolled Chinese Academy of Medical Sciences
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to determine whether Intensity-modulated radiation therapy (IMRT) combined inductive and concurrent chemotherapy with more intensive regimen (cisplatin and paclitaxel) is feasible and effective than current standard treatment for high-risk locally advanced NPC patients.

Timeline

Start
2013-03
Primary completion
2014-09
Completion
2014-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Cisplatin Other / unclassified 75 mg/m2 —
Subject Cisplatin Other / unclassified 80 mg/m2 —
Subject Cisplatin Other / unclassified 100 mg/m2 —
Subject Paclitaxel Small molecule 175 mg/m2 —

Indications

nasopharyngeal carcinoma