The Impact of Actos Treatment of Diabetes on Glucose Transporters in Muscle

Summary

Subjects with type 2 diabetes will be treated with Actos or placebo for eight weeks and needle biopsies of muscle will quantify changes in any of seven different glucose transport proteins in muscle.

Timeline

Start

2002-03

Primary completion

2004-03

Completion

2004-03

Publications

• Results Stuart CA, Howell ME, Yin D. Overexpression of GLUT5 in diabetic muscle is reversed by pioglitazone. Diabetes Care. 2007 Apr;30(4):925-31. doi: 10.2337/dc06-1788. Epub 2007 Jan 24.

Drugs

Indications