drugset / Trial / NCT01804049
Metformin and Muscle in Insulin-resistant Older Veterans
Phase 1/2
Completed
120 enrolled
VA Office of Research and Development
Oregon Health and Science University · collab
RandomizedParallel-groupDouble-blindOther
Summary
Sarcopenia is the loss of muscle mass, strength and function with aging and is associated with increased disability, falls and fractures. Older adults with diabetes and prediabetes are insulin resistant and have a higher risk of developing sarcopenia. This study examines the use of metformin, an antidiabetic drug, for preventing the development of sarcopenia in older adults with prediabetes.
Timeline
- Start
- 2014-04-08
- Primary completion
- 2018-08-31
- Completion
- 2018-08-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Metformin | Small molecule | 850 mg | Oral |