drugset / Trial / NCT01804049

Metformin and Muscle in Insulin-resistant Older Veterans

NCT01804049

RandomizedParallel-groupDouble-blindOther

Summary

Sarcopenia is the loss of muscle mass, strength and function with aging and is associated with increased disability, falls and fractures. Older adults with diabetes and prediabetes are insulin resistant and have a higher risk of developing sarcopenia. This study examines the use of metformin, an antidiabetic drug, for preventing the development of sarcopenia in older adults with prediabetes.

Timeline

Start
2014-04-08
Primary completion
2018-08-31
Completion
2018-08-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Metformin Small molecule 850 mg Oral

Indications