drugset / Trial / NCT01807429
Is Analgesic Effect of Low Dose Ketamine-midazolam the Same as Morphine
RandomizedParallel-groupSingle-blindTreatment
Summary
the investigators assessed the effects of low-dose IV ketamine-midazolam versus morphine on pain control in trauma patients with closed limb fracture(s); and also compared the incidence of adverse events (mainly cardio pulmonary ) between two groups.
Timeline
- Start
- 2012-12
- Primary completion
- 2013-01
- Completion
- 2013-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketamine | Small molecule | 300 ug/kg | Intravenous |
| Subject | Ketamine | Small molecule | 500 ug/kg | Intravenous |
| Comparator | Morphine | Other / unclassified | 0.05 mg/kg | Intravenous |
| Comparator | Morphine | Other / unclassified | 0.1 mg/kg | Intravenous |
| Background | Midazolam | Small molecule | 0.03 mg/kg | Intravenous |