drugset / Trial / NCT01810315
Influence of Reproductive Cycle and Menopause on HIV-1 Infection and TFV Gel Activity
Non-randomizedCrossoverOpen-label
Summary
Purpose of the study is to assess tenofovir (TFV) PK and PD endpoints, cervicovaginal safety parameters, susceptibility to HIV-1 infection, and objective measures of vaginal applicator use in premenopausal and postmenopausal women.
Timeline
- Start
- 2013-09
- Primary completion
- 2014-10
- Completion
- 2014-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tenofovir | Small molecule | 4.4 g | Other |
| Background | Estradiol | Other / unclassified | 1 g | Other |
Indications
No indication recorded.