drugset / Trial / NCT01817972
Cimzia Versus Cimzia Plus Azathioprine in the Treatment of Active Crohn's Disease
RandomizedParallel-groupTriple-blindTreatment
Summary
This is a randomized, double blind trial of combination therapy (Cimzia plus Azathioprine) versus mono therapy (Cimzia alone) and the improvement in mean SES-CD (Simple Endoscopic Scoring in Crohn's Disease) score. It is a trial where the investigators are administering biological therapy by itself and biological therapy plus an immunosuppressive medicine in combination to see which form of therapy has a better effect on healing ulcerations in the small intestine and colon that are due to a flare up of Crohn's disease.
Timeline
- Start
- 2013-03
- Primary completion
- 2014-06
- Completion
- 2014-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Azathioprine | Small molecule | 1.5 mg/kg | Oral |
| Comparator | Certolizumab Pegol | Protein / enzyme biologic | 400 mg | Subcutaneous |