drugset / Trial / NCT01817972

Cimzia Versus Cimzia Plus Azathioprine in the Treatment of Active Crohn's Disease

NCT01817972

RandomizedParallel-groupTriple-blindTreatment

Summary

This is a randomized, double blind trial of combination therapy (Cimzia plus Azathioprine) versus mono therapy (Cimzia alone) and the improvement in mean SES-CD (Simple Endoscopic Scoring in Crohn's Disease) score. It is a trial where the investigators are administering biological therapy by itself and biological therapy plus an immunosuppressive medicine in combination to see which form of therapy has a better effect on healing ulcerations in the small intestine and colon that are due to a flare up of Crohn's disease.

Timeline

Start
2013-03
Primary completion
2014-06
Completion
2014-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator Azathioprine Small molecule 1.5 mg/kg Oral
Comparator Certolizumab Pegol Protein / enzyme biologic 400 mg Subcutaneous

Indications