drugset / Trial / NCT01838538

Clinical Study in Treatment of Malignant Ascites of Ovarian Cancer With Intraperitoneal Injection Bevacizumab Combined With Intraperitoneal Hyperthermic Perfusion Chemotherapy

NCT01838538 ↗

Phase 2 Unknown 54 enrolled Chinese PLA General Hospital
Non-randomizedParallel-groupOpen-labelTreatment

Summary

To study the efficacy and safety of intraperitoneal injection bevacizumab combined with intraperitoneal hyperthermic perfusion chemotherapy in treatment of malignant ascites of ovarian cancer. To analyze the clinical significance of the concentration change of vascular endothelial growth factor (VEGF) in ascites in treatment of intraperitoneal injection bevacizumab

Timeline

Start
2011-06
Primary completion
2013-06
Completion
—

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 300 mg Other
Background Carboplatin Small molecule 5 unknown Intravenous
Background Paclitaxel Small molecule 135 mg/m2 Intravenous

Indications