Efficacy and Safety Study of Sodium Phosphate Tablets vs PEG for Bowel Cleansing

Phase 3 Completed 461 enrolled Laboratoires Mayoly Spindler

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the efficacy and safety of sodium phosphate tablets compared to split dose of 4 liters of PEG used in adults for bowel cleansing prior to colonoscopy.

Timeline

Start: 2013-05
Primary completion: 2014-03
Completion: 2014-03

Outcome

Met primary endpoint

paper In all segment (right colon, transverse colon and left colon and rectum), the NaP group was non-inferior to the PEG group. PMID 27864718 ↗

Publications

Chaussade S, Schmocker C, Toulemonde P, Munoz-Navas M, O'Mahony V, Henri F. Phosphate tablets or polyethylene glycol for preparation to colonoscopy? A multicentre non-inferiority randomized controlled trial. Surg Endosc. 2017 May;31(5):2166-2173. doi: 10.1007/s00464-016-5214-1. Epub 2016 Nov 18.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	polyethylene glycol	Other / unclassified	4000 ml	—
Subject	sodium phosphate	Unknown	—	Oral

Indications

No indication recorded.