drugset / Trial / NCT01845090
The Effect of Lanthanum Carbonate on Fibroblast Growth Factor 23
RandomizedParallel-groupSingle-blindTreatment
Summary
To compare the effect of lanthanum carbonate with calcium carbonate on serum FGF23 levels in hemodialysis patients.
Timeline
- Start
- 2011-08
- Primary completion
- 2014-07
- Completion
- 2014-07
Publications
- Natale P, Green SC, Ruospo M, Craig JC, Vecchio M, Elder GJ, Strippoli GF. Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD). Cochrane Database Syst Rev. 2025 Jun 27;6(6):CD006023. doi: 10.1002/14651858.CD006023.pub4.
- Chang YM, Tsai SC, Shiao CC, Liou HH, Yang CL, Tung NY, Hsu KS, Chen IL, Liu MC, Kao JL, Jhen RN, Huang YT. Effects of lanthanum carbonate and calcium carbonate on fibroblast growth factor 23 and hepcidin levels in chronic hemodialysis patients. Clin Exp Nephrol. 2017 Oct;21(5):908-916. doi: 10.1007/s10157-016-1362-9. Epub 2016 Dec 7.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Calcium carbonate | Other / unclassified | 500 mg | — |
| Comparator | Calcium carbonate | Other / unclassified | 1000 mg | — |
| Comparator | Lanthanum Carbonate | Other / unclassified | 375 mg | — |
| Comparator | Lanthanum Carbonate | Other / unclassified | 750 mg | — |
Indications
No indication recorded.