drugset / Trial / NCT01849770
Mexiletine in Sporadic Amyotrophic Lateral Sclerosis (SALS)
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this research is to find out if mexiletine is safe and effective in people with Amyotrophic Lateral Sclerosis (ALS). In this trial, participants will be taking either 300 milligrams per day of mexiletine, 900 milligrams per day of mexiletine or placebo (non-active study drug). The safety and efficacy of these doses will be compared to see if one dose is better than the other.
Timeline
- Start
- 2013-07
- Primary completion
- 2014-08
- Completion
- 2014-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Mexiletine | Small molecule | 300 mg | Oral |
| Comparator | Mexiletine | Small molecule | 900 mg | Oral |