drugset / Trial / NCT01849770

Mexiletine in Sporadic Amyotrophic Lateral Sclerosis (SALS)

NCT01849770

Phase 2 Completed 75 enrolled University of Washington
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this research is to find out if mexiletine is safe and effective in people with Amyotrophic Lateral Sclerosis (ALS). In this trial, participants will be taking either 300 milligrams per day of mexiletine, 900 milligrams per day of mexiletine or placebo (non-active study drug). The safety and efficacy of these doses will be compared to see if one dose is better than the other.

Timeline

Start
2013-07
Primary completion
2014-08
Completion
2014-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Mexiletine Small molecule 300 mg Oral
Comparator Mexiletine Small molecule 900 mg Oral