drugset / Trial / NCT01851486
The Relationships Between the Noradrenergic, Opioid and Pain System
Withdrawn
Rambam Health Care Campus
RandomizedParallel-groupDouble-blindBasic science
Summary
The role of alpha2 receptor agonist on pain perception and modulation will be examined. In addition whether this is mediated through the opioid system will be examined. Pain perception and modulation will be examined before and after administration of Clonidine or placebo together with Naloxone or saline.
Timeline
- Start
- 2013-01
- Primary completion
- 2016-09
- Completion
- 2016-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Clonidine | Other / unclassified | 0.15 mg | — |
| Comparator | Naloxone | Small molecule | 0.15 mg/kg | — |
Indications
No indication recorded.