drugset / Trial / NCT01859455
Safety, Pharmacokinetics and Pharmacodynamics of LGT209 in Healthy Volunteers With Elevated Cholesterol and in Hypercholesterolemic Patients Treated With Statins
RandomizedParallel-groupDouble-blindTreatment
Summary
This study is designed to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of LGT209 in hypercholesterolemic patients taking common statin medications and in healthy volunteers.
Timeline
- Start
- 2011-07
- Primary completion
- 2012-07
- Completion
- 2012-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | LGT209 | Unknown | 50 mg | Subcutaneous |
| Subject | LGT209 | Unknown | 300 mg | Subcutaneous |
| Background | Atorvastatin | Small molecule | — | — |
| Background | Simvastatin | Small molecule | — | — |