drugset / Trial / NCT01862835
Impact of Estradiol Addback
RandomizedCrossoverTriple-blindBasic science
Summary
Repletion of testosterone (T) in older men drives Growth Hormone secretion after its aromatization to estradiol (E2) by potentiating endogenous GH drive.
Timeline
- Start
- 2013-05
- Primary completion
- 2016-09-30
- Completion
- 2018-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Anastrozole | Other / unclassified | 2 mg | Oral |
| Subject | Estradiol | Other / unclassified | 0.05 mg | Other |
| Subject | Testosterone | Small molecule | 100 mg | Intramuscular |
| Background | Degarelix | Other / unclassified | 80 mg | Subcutaneous |
Indications
No indication recorded.