drugset / Trial / NCT01871558
Vildagliptin/Metformin in T2DM Patients Starting Basal Insulin
RandomizedParallel-groupOpen-labelTreatment
Summary
To compare a therapeutic strategy combining vildagliptin+metformin + Basal Insulin versus SU+metformin + Basal Insulin on the incidence of hypoglycemic events over 24 weeks.
Timeline
- Start
- 2013-06
- Primary completion
- 2015-02
- Completion
- 2015-02
Outcome
Missed primary endpoint
registry analysis (superiority or other test); Metformin/Vildagliptin + Basal Insulin vs SU+Metformin + Basal Insulin; p = 0.139; Chi-squared NCT01871558 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Vildagliptin | Other / unclassified | 50 mg | — |
| Background | Metformin | Small molecule | — | — |