drugset / Trial / NCT01886209
Phase 1 PK Interaction Study Between VX-509 and Prednisone or Methylprednisolone in Healthy Male Subjects
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This study is designed to evaluate the effect of VX-509 on the pharmacokinetics (PK) of corticosteroids (prednisone or methylprednisolone) and the effect of corticosteroids on the PK of VX-509 and its metabolite. The study will also evaluate the safety and tolerability of VX-509 when coadministered with each of these corticosteroids.
Timeline
- Start
- 2013-06
- Primary completion
- 2013-08
- Completion
- 2013-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methylprednisolone | Other / unclassified | 8 mg | — |
| Subject | Prednisone | Other / unclassified | 10 mg | — |
| Subject | decernotinib | Small molecule | 200 mg | — |
Indications
No indication recorded.