drugset / Trial / NCT01894685

Mesalazine Effects in Sporadic Colorectal Adenoma Patients

NCT01894685

Phase 2 Completed 74 enrolled UMC Utrecht
RandomizedParallel-groupQuadruple-blindPrevention

Summary

Several studies indicate that mesalazine might have a preventive effect on recurrence of adenomas in patients with and without inflammatory bowel disease. As mesalazine has limited adverse effects, it is an attractive candidate for chemoprevention. In this study we aim to investigate the antineoplastic properties of mesalazine in patients with sporadic colorectal adenomas.

Timeline

Start
2012-07
Primary completion
2015-06
Completion
2015-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Mesalamine Small molecule 3 g

Indications