Efficacy of Latanoprostene Bunod in Lowering Intraocular Pressure in Japanese Healthy Male Volunteers

Phase 1 Completed 24 enrolled Bausch & Lomb Incorporated

NaSingle-groupOpen-labelTreatment

Summary

The objective of this study is to evaluate the effect of latanoprostene bunod dosed once daily (QD) in reducing intraocular pressure (IOP) measured over a 24-hour period in healthy subjects.

Timeline

Start: 2013-07
Primary completion: 2013-08
Completion: 2013-10

Publications

Results Araie M, Sforzolini BS, Vittitow J, Weinreb RN. Evaluation of the Effect of Latanoprostene Bunod Ophthalmic Solution, 0.024% in Lowering Intraocular Pressure over 24 h in Healthy Japanese Subjects. Adv Ther. 2015 Nov;32(11):1128-39. doi: 10.1007/s12325-015-0260-y. Epub 2015 Nov 12.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Latanoprostene bunod	Small molecule	0.024 %	Topical

Indications

No indication recorded.