drugset / Trial / NCT01897012

Alisertib and Romidepsin in Treating Patients With Relapsed or Refractory B-Cell or T-Cell Lymphomas

NCT01897012

Phase 1 Completed 26 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase I trial studies the side effects and best dose of alisertib and romidepsin in treating patients with B-cell or T-cell lymphomas that have returned after a period of improvement (relapsed) or have not responded to treatment (refractory). Alisertib and romidepsin may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2013-07-17
Primary completion
2018-10-31
Completion
2018-11-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Alisertib Small molecule Oral
Subject Romidepsin Peptide Intravenous