Phase 1 34 trials
Phase 1
NCT04479306
Jun 2020 → Jul 2023
non-small cell lung carcinoma
M.D. Anderson Cancer Center
Completed
No outcome recorded
Phase 1
NCT04085315
Nov 2019 → Dec 2026 expected
lung cancer
Collin Blakely
Recruiting
No outcome recorded
Phase 1
NCT02700022
Oct → Nov 2016
Burkitt lymphoma , diffuse large B-cell lymphoma , follicular lymphoma
UNC Lineberger Comprehensive Cancer Center
Terminated
No outcome recorded
Phase 1
NCT02812056
Sep 2016 → Sep 2021
digestive system cancer , female reproductive organ cancer , head and neck cancer , male reproductive organ cancer
M.D. Anderson Cancer Center
Withdrawn
No outcome recorded
Phase 1
NCT02719691
May 2016 → Mar 2020
breast cancer
University of Colorado, Denver
Completed
No outcome recorded
Phase 1
NCT02780011
Dec 2015 → Sep 2018
non-Hodgkin lymphoma
Eric Bernicker, MD
Withdrawn
No outcome recorded
Phase 1
NCT02551055
Oct 2015 → Feb 2017
adenocarcinoma
Millennium Pharmaceuticals, Inc.
Terminated
No outcome recorded
Phase 1
NCT02319018
Aug 2015 → Sep 2018
digestive system cancer
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT02367352
Mar 2015 → May 2017
ovarian cancer , small cell lung carcinoma
Millennium Pharmaceuticals, Inc.
Terminated
No outcome recorded
Phase 1
NCT02186509
Jan 2015 → Mar 2017
adult anaplastic ependymoma , adult brainstem glioma , adult glioblastoma , adult oligodendroglioma +8
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Completed
No outcome recorded
Phase 1
NCT02327169
Jan 2015 → Jul 2018
neoplastic disease or syndrome
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 1
NCT02219789
Dec 2014 → Mar 2016
estrogen-receptor positive breast cancer , female breast carcinoma , progesterone-receptor positive breast cancer
Mayo Clinic
Completed
No outcome recorded
Phase 1
NCT02259010
Oct 2014 → Mar 2015
lymphoma
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 1
NCT02214147
Aug 2014 → Apr 2016
cancer , lymphoma
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 1
NCT01639911
Aug 2013 → Jul 2016
breast cancer , central nervous system cancer , digestive system cancer , head and neck neoplasm +2
University of Illinois at Chicago
Completed
No outcome recorded
Phase 1
NCT01924260
Aug 2013 → Feb 2017
pancreatic acinar cell carcinoma , pancreatic ductal adenocarcinoma
Edward Kim
Completed
No outcome recorded
Phase 1
NCT01923337
Aug 2013 → Oct 2016
colon mucinous adenocarcinoma , colon signet ring cell adenocarcinoma , rectal signet ring cell adenocarcinoma , rectum mucinous adenocarcinoma
University of California, Davis
Completed
No outcome recorded
Phase 1
NCT01613261
Aug 2013 → Sep 2015
neoplasm
Millennium Pharmaceuticals, Inc.
Withdrawn
No outcome recorded
Phase 1
NCT01897012
Jul 2013 → Oct 2018
Burkitt lymphoma , Hodgkins lymphoma , diffuse large B-cell lymphoma , follicular lymphoma +3
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT01898078
Jul 2013 → Mar 2014
cancer , lymphoma
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 1
NCT01844583
Jun 2013 → Aug 2014
cancer , lymphoma
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 1
NCT01677559
May 2013 → Sep 2014
adenocarcinoma , pancreatic neoplasm
Washington University School of Medicine
Completed
No outcome recorded
Phase 1
NCT01779843
Apr 2013 → Nov 2015
acute myeloid leukemia
Massachusetts General Hospital
Completed
No outcome recorded
Phase 1
NCT01714947
Jan → Apr 2013
cancer , lymphoma
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 1
NCT01695941
Aug 2012 → May 2018 overdue
mantle cell lymphoma
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 1
NCT01567709
Apr 2012 → Mar 2018
B-cell adult acute lymphocytic leukemia , Burkitt lymphoma , Hodgkins lymphoma , MALT lymphoma +19
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT01512758
Feb 2012 → Oct 2013
cancer , lymphoma
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 1
NCT01540682
Feb 2012 → Nov 2015
head and neck squamous cell carcinoma
Abramson Cancer Center at Penn Medicine
Completed
No outcome recorded
Phase 1
NCT01094288
Aug 2010 → Feb 2014
prostate adenocarcinoma
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 1
NCT00962091
Sep 2009 → Dec 2011
cancer
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 1
NCT02444884
Sep 2008 → Dec 2011
childhood malignant neoplasm , neuroblastoma
Children's Oncology Group
Completed
No outcome recorded
Phase 1
NCT00697346
Jul 2008 → Oct 2016
Waldenstrom macroglobulinemia , anaplastic large cell lymphoma , angioimmunoblastic T-cell lymphoma , chronic lymphocytic leukemia/small lymphocytic lymphoma +7
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 1
NCT00651664
Oct 2007 → Sep 2010
cancer
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 1
NCT00500903
May 2007 → Aug 2010
cancer
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Show 24 more trials
Phase 1/2 7 trials
Phase 1/2
NCT04555837
Sep 2020 → Apr 2025
head and neck squamous cell carcinoma
M.D. Anderson Cancer Center
Completed
No outcome recorded
Phase 1/2
NCT01848067
Aug 2013 → Mar 2015
hormone-resistant prostate carcinoma , prostate adenocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Completed
No outcome recorded
Phase 1/2
NCT01601535
May 2012 → Jul 2018
neuroblastoma
New Approaches to Neuroblastoma Therapy Consortium
Completed
No outcome recorded
Phase 1/2
NCT01471964
Oct 2011 → Feb 2017
non-small cell lung carcinoma
Fox Chase Cancer Center
Terminated
No outcome recorded
Phase 1/2
NCT01397825
Aug 2011 → Feb 2015
Burkitt lymphoma , diffuse large B-cell lymphoma , mantle cell lymphoma
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 1/2
NCT01045421
Feb 2010 → May 2013
breast cancer , gastroesophageal adenocarcinoma , head and neck squamous cell carcinoma , non-small cell lung carcinoma +1
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 1/2
NCT01034553
Feb 2010 → Sep 2014
plasma cell myeloma
Mayo Clinic
Completed
No outcome recorded
Phase 2 22 trials
Phase 2
NCT07465757
Sep 2026 → Mar 2028 expected
small cell lung carcinoma
Puma Biotechnology, Inc.
Not yet recruiting
No outcome recorded
Phase 2
NCT07706179
Aug 2026 → Aug 2028 expected
hormone receptor-positive breast cancer
University of Wisconsin, Madison
Not yet recruiting
No outcome recorded
Phase 2
NCT06369285
Nov 2024 → Jun 2027 expected
hormone receptor-positive breast cancer
Puma Biotechnology, Inc.
Recruiting
No outcome recorded
Phase 2
NCT06095505
Feb 2024 → Oct 2027 expected
small cell lung carcinoma
Puma Biotechnology, Inc.
Recruiting
No outcome recorded
Phase 2
NCT02860000
Jul 2017 → Jan 2022
Her2-receptor negative breast cancer , estrogen-receptor positive breast cancer , female breast carcinoma , invasive breast carcinoma
Mayo Clinic
Completed
No outcome recorded
Phase 2
NCT02560025
Dec 2015 → Oct 2017
acute myeloid leukemia
Massachusetts General Hospital
Completed
No outcome recorded
Phase 2
NCT02293005
May 2015 → Jul 2021
lung cancer , mesothelioma
M.D. Anderson Cancer Center
Completed
No outcome recorded
Phase 2
NCT02187991
Feb 2015 → Apr 2024
breast carcinoma
US Oncology Research
Completed
No outcome recorded
Phase 2
NCT02109328
Aug 2014 → Jul 2015
transitional cell carcinoma , urinary bladder cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Completed
No outcome recorded
Phase 2
NCT02114229
May 2014 → Sep 2025 overdue
atypical teratoid rhabdoid tumor
St. Jude Children's Research Hospital
Active not recruiting
No outcome recorded
Phase 2
NCT02038647
May 2014 → Jan 2016
small cell lung carcinoma
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 2
NCT01812005
May 2013 → Oct 2015
Burkitt lymphoma , MALT lymphoma , Waldenstrom macroglobulinemia , diffuse large B-cell lymphoma +3
Ohio State University Comprehensive Cancer Center
Terminated
No outcome recorded
Phase 2
NCT01799278
Feb 2013 → Jul 2016
prostate small cell carcinoma
Weill Medical College of Cornell University
Completed
No outcome recorded
Phase 2
NCT01653028
Aug 2012 → Aug 2015
leiomyosarcoma , liposarcoma , malignant peripheral nerve sheath tumor , myxofibrosarcoma +1
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT01637961
Aug 2012 → Aug 2014
leiomyosarcoma of the corpus uteri
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT01316692
Oct 2011 → Nov 2014
metastatic melanoma
Vanderbilt-Ingram Cancer Center
Terminated
No outcome recorded
Phase 2
NCT01466881
Oct 2011 → Dec 2014
adult T-cell leukemia/lymphoma , anaplastic large cell lymphoma , angioimmunoblastic T-cell lymphoma , extranodal nasal NK/T cell lymphoma +1
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT01154816
Feb 2011 → Dec 2015
Ewing sarcoma/peripheral primitive neuroectodermal tumor , childhood acute lymphoblastic leukemia , childhood acute myeloid leukemia , childhood kidney neoplasm +5
Children's Oncology Group
Completed
No outcome recorded
Phase 2
NCT01091428
Apr 2010 → Aug 2014
breast carcinoma , fallopian tube cancer , ovarian carcinoma , peritoneum cancer
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 2
NCT00853307
Mar → Nov 2009
ovarian carcinoma
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 2
NCT00807495
Feb 2009 → Jan 2011
Burkitt lymphoma , T-cell non-Hodgkin lymphoma , diffuse large B-cell lymphoma , mantle cell lymphoma
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase 2
NCT00830518
Feb 2009 → Feb 2010
acute myeloid leukemia , myelodysplastic syndrome
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Show 12 more trials
Phase 3 1 trial
Phase 3
NCT01482962
Jun 2012 → Jun 2015
peripheral T-cell lymphoma, not otherwise specified
Millennium Pharmaceuticals, Inc.
Completed
No outcome recorded
Phase not applicable 1 trial
—
NCT02530619
Oct 2015 → May 2018
acute megakaryoblastic leukemia , myelofibrosis , primary myelofibrosis
Northwestern University
Unknown
No outcome recorded