drugset / Trial / NCT02259010
A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of Alisertib in Participants With Advanced Solid Tumors or Relapsed/Refractory Lymphoma
NaSingle-groupOpen-labelBasic science
Summary
This study will assess the effect of multi-dose administration of itraconazole on the single-dose pharmacokinetics (PK) of alisertib.
Timeline
- Start
- 2014-10-22
- Primary completion
- 2015-03-27
- Completion
- 2016-10-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Alisertib | Small molecule | 30 mg | Oral |
| Subject | Alisertib | Small molecule | 50 mg | Oral |
| Subject | Itraconazole | Small molecule | 200 mg | Oral |