drugset / Trial / NCT01899326
Desipramine Hydrochloride and Filgrastim For Stem Cell Mobilization in Patients With Multiple Myeloma Undergoing Stem Cell Transplant
NaSingle-groupOpen-labelTreatment
Summary
This pilot clinical trial studied how well desipramine hydrochloride and filgrastim worked for stem cell mobilization in participants with multiple myeloma (MM) undergoing stem cell transplant. Giving colony-stimulating factors, such as filgrastim, and other drugs, such as desipramine hydrochloride, helps stem cells move from the participant's bone marrow to the blood so they can be collected and stored.
Timeline
- Start
- 2013-09
- Primary completion
- 2015-03
- Completion
- 2015-03
Outcome
Outcome not reported
Stopped (Enrollment): “The study was stopped during the interim analysis due to low accrual after the widespread use of plerixafor for multiple myeloma in the United States.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Desipramine | Small molecule | — | Oral |
| Subject | filgrastim | Protein / enzyme biologic | — | Oral |